Tadacip

Tadacip is an oral drug indicated in the treatment of men with erectile dysfunction (ED), which corresponds to the inability to obtain or maintain a sufficient penile erection for satisfactory sexual activity. Sexual stimulation is required to achieve the effectiveness of Tadacip.

Tadacip is a generic version of Cialis, a widely popular “weekend pill” and the principal competitor of Viagra, the first oral solution to address the issue of ED. The scientific rationale behind the pill’s moniker is the heavy-duty format of its action: the drug’s effect last during 36 hours. Another major advantage of tadalafil as a representative of its class is its famed compatibility with alcohol. Alongside the same lines, tadalafil action is unaffected by bulky or fatty meals, which is yet another benefit that tips the scales in favor of pharmaceutical products based on tadalafil, such as Tadacip.

Tadalafil is an inhibitor of phosphodiesterase type 5 (PDE5). The absorption, elimination, metabolism and half-life of a product are important parameters as they determine the mode of administration of the product and the number of daily doses, in order to maintain the effectiveness of the treatment.

These products are easily absorbed and the plasma peak is reached in 1 to 2 hours fasting, delayed one hour by a fatty meal, except for tadalafil. They are metabolized by the liver, elimination is mainly bilio-fecal (80%) and urinary elimination half-life is about 17 hours for tadalafil and 5 hours for sildenafil and vardenafil. These different pharmacokinetic parameters allow one daily intake on an empty stomach or during a meal, depending on the products, 30 for tadalafil to 60 minutes before sexual activity.

The advantages of Cialis as a product based on tadalafil are numerous and well documented, but the drug has a serious downside, and it is its price. Featuring a prolonged action and a number of other benefits noted above in this Tadacip review, Cialis retails at a price that makes it economically unavailable for shoppers on a budget. In this connection, generic Cialis is an ultimately practical solution that provides the benefits of the original drug with none of its prohibitive cost incurred.

The challenge with a decision to buy generic Cialis online is finding an e-pharmacy that deals with registered and reliable drug manufacturers. Look for Tadacip manufactured by Cipla Ltd, a reputable pharmaceutical company in the pharmaceutical industry that is part of the BSE Sensex stock market index. Cipla was created in 1935. In 2013, Cipla acquired the South African company Medpro. In September 2015, Cipla acquired InvaGen Pharmaceuticals and Exelan Pharmaceuticals, two US pharmaceutical companies.

Tadacip produced by Cipla Ltd is manufactured with high quality ingredients according to international drug production standards. The safety and the efficacy of the drug is analogous to that of the original Cialis produced by Eli Lilly.

Tadacip is taken as needed, prior to sexual activity. Take a tablet with a glass of water no sooner than 30 minutes before engaging sexually. Do not crush or chew the tablet. Do not take more than one recommended dose within 24 hours’ period.

The dossier filed with the European Medicines Agency contains several studies against placebo. The first in general population, the second for diabetics, and the third after prostatectomy. Erectile dysfunction very often has a significant psychological component, it is not surprising that the percentage of patients managing to “maintain an erection sufficient to achieve penetration” is doubled, from 12 to 27%, with a simple placebo. With a dose of tadalafil 5 mg, it is tripled (41%) and is quadrupled at a dose of 100 mg (5772% of patients who used the 200 mg dose felt that the drug had improved their erection (versus 26% on placebo), more than the 100 mg (61%) and 50 mg (52%) group. The effect of the 20 mg tablet (eg, Tadacip) was also more prolonged over time, as it persisted for more than 42 hours after dosing, whereas the effect declined sharply after 36 hours at 10 mg and 28 minutes at 5 mg.

Forzest is a drug whose composition (save for excipients) is identical to that of Tadacip. Both pills contain 20 mg of the active substance tadalafil. The two generics of Cialis have different manufacturers, and the only, rather subjective, difference between the two of them is which manufacturer evokes more trust in customers.

Tadacip is produced by the Indian pharmaceutical company Cipla Ltd, while Forzest is manufactured by Ranbaxy Laboratories. Both drugs share a common country of origin.

Ranbaxy Laboratories is an Indian company established in 1961 and since that time has become one of the leading generics companies. In April 2014, Sun Pharmaceutical acquired Ranbaxy for $ 3.2 billion, previously held by Daiichi Sankyo at 63.9%, creating the largest Indian pharmaceutical company. Through its revenues, it is one of the ten largest Indian pharmaceutical companies.

The dilemma of choosing between tadalafil and sildenafil (the non-proprietary name of Viagra) is as old as tadalafil itself (the formula of that latter was developed in 2003). The choice is seemingly simple and can be illustrated by the facts displayed in the table below:

Tadacip Vs. Viagra: Essential Differences

However, one should take into account individual response and tolerance, as well as changing circumstances. Patients who respond well to either of the two substances can choose whichever appeals most to them, based on the needs of the moment – and the price, for it is a crucial parameter factoring heavily in. One should never use both drugs on the same day though.

According to reports and as is seen from patient-years of application of both tadalafil and sildenafil, one of these substances always evokes a better response in the same user. It is a general recommendation to try both pills on several different occasions in order to establish which tablet provides more meaningful health outcomes.

In fact, when you look at the medication leaflet, the differences between Tadacip and its competitors (Forzest, Cialis, Apcalis) are not obvious. In addition, there is no comparative study between tadalafil and other drugs of the same family. Indeed, for a drug to be approved, it is enough for it to do better than a placebo (fake drug used without the knowledge of a guinea pig to take into account the “psychological” effect of taking a drug supposed active), provided of course that active treatment is not essential. An antibiotic is for example tested against a reference antibiotic, but in no case against a placebo.

Tadacip and Apcalis are identical and therefore fully interchangeable drugs, but they differ in form. Apcalis is manufactured in form of gel for peroral use and comes in sachets containing the same amount of tadalafil as Tadacip, which is 20 mg. It is therefore a matter of personal preference – tablet haters will benefit from availability of tadalafil in this congenial rendition that also comes with fresh fruity flavor. It is also believed that a gel form of the drug promotes faster uptake, which in case of tadalafil has no significant difference and is a matter of but a few minutes of difference.

Tadacip is compatible with alcohol, but only to the extent that the drug efficiency is not compromised by hard drinks taken alongside with it. However, it is not recommended to consume alcohol prior to engaging sexually, especially in the presence of erectile difficulty. If a few glasses have the effect of relaxing our nerves and making us more sociable, alcohol abuse has unpleasant consequences on erectile function. Several factors are involved. The more alcohol in the blood, the more sexual stimulation of the brain and nervous system becomes ineffective. The ability to reach orgasm, to breathe well and to have an erection is heavily affected.

These are some complications that can occur when taking the drug, knowing that the side effects induced vary by individual. The most commonly reported adverse reactions when taking Tadacip:

• headache
• redness
• dyspepsia
• blurred vision
• nasal congestion
• dizziness and impaired color vision
• arthralgia
• myalgia

There is a discreet decrease in blood pressure, which can be aggravated by taking certain products, including nitrates. Rarely, photosensitization reactions, serious cardiovascular events have been reported, particularly in at-risk subjects with myocardial infarction, unstable angina, ventricular arrhythmias, ischemic cerebral events. Priapisms cases have also been reported.